

Mission
Catalyst Biosciences is developing the next generation of biopharmaceuticals by harnessing the catalytic power of proteases.
Overview
Founded in 2003, Catalyst Biosciences, Inc., is a leading
biotechnology company focused on developing proteases as a therapeutic
platform for inflammation, cardiovascular, and angiogenesis-based disorders.
Proteases are well established as a class of drugs, with over 7 protease
drugs on the market and over $3 billion in annual sales. Catalyst is
developing and intends to market both natural and engineered human
proteases ("Alterases™") to treat major diseases. By
engineering human proteases to alter their substrate specificity so
that they can inactivate any given protein target, Catalyst will vastly
increase the use and application for therapeutic proteases, and create
a new paradigm in target intervention. The company believes that the
ability to target any soluble or cell surface protein involved in disease
via an Alterase represents a significant opportunity for drug development,
akin in breadth and potential value to that offered by monoclonal antibodies.
Catalyst has assembled a team of world-class scientists and advisors,
an enabling technology platform, and a robust pipeline, and is thus
poised to become a fully integrated biopharmaceutical company with
a diversified portfolio.



